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Allergen Focus

In 1998, Mayo Clinic transformed the management of skincare product allergen avoidance with the launch of the Contact Allergen Replacement Database (CARD)
Allergic contact dermatitis (ACD) affects over 14.5 million Americans each year, notably defining itself as an important widespread disease.
Pediatric contact dermatitis has become an increasingly recognized entity in the last decade, with recent pediatric contact allergy estimates ranging from 41% to 77% in those referred for patch testing.
MP, aka balsam of Peru (BOP), has remained 1 of the 5 most prevalent allergens detected by both the thin-layer rapid use epicutaneous (TRUE) test and the North American Contact Dermatitis Group over the last decade.6,7 Notably, the first cutaneous allergic manifestation was described by Mögling in 1880, well after it had been used in Europe for over 300 years.8 
Sharon E. Jacob, MD
Lanolin is routinely found in a wide range of products from metal lubricants and rust preventers to skincare emollient, wound care products and a vehicle for topical therapeutics (Table 1). This has lead to lanolin making the “A-List” for top allergens. The 4 characteristics of lanolin contribute to the difficulty in determining its relevance as an allergen.
Nurses can play a critical role in all phases of patch testing, which can improve the outcome for patients with dermatitis.
Diaper dermatitis is a very broad term, encompassing a variety of skin conditions and is one of the most common cutaneous disorders of infancy. In general, the overall incidence is between 7% and 35% with a peak at 9 to 12 months of age.9 An infant’s anatomy can be a predisposing risk factor in and of itself, as the many folds and creases constitute areas of difficulty for cleansing and contribute to a moist environment.10 A thorough patient history is a key component in making the proper diagnosis.11 
Personal care products and topical medicaments, especially topical corticosteroids, are the most common sources of PG allergy.
Photo-allergic contact dermatitis is uncommon. The diagnosis requires a complete patient history and exclusion of other dermatoses.
Allergic contact dermatitis of the anogenital region is uncommon, but it is a significant cause of discomfort for those afflicted, making proper diagnosis of utmost importance.
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