Redesigned Pulsed Dye Laser Therapy Studied for Efficacy in Rosacea

04/24/2018
Dr Bernstein

A redesigned pulsed dye laser (PDL), which included a newly designed laser cavity with a 15-mm diameter treatment beam, effectively reduced signs of erythemato‐telangiectatic rosacea, according to the findings of a recent study by Bernstein and colleagues, published in Lasers in Surgery and Medicine.

The study included 19 participants with erythemato‐telangiectatic rosacea. Participants underwent 4 monthly treatments of PDL, which first targeted linear vessels with a 3x10 mm elliptical beam then targeted diffuse redness with a 15-mm diameter circular beam. Photographs of the participants were taken at baseline and 2 months after the last treatment with a 11-point clearance scale. Three blinded reviewers were asked to identify baseline photos from post-treatment photos and to rate improvement of rosacea.
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Overall, blinded reviewers correctly identified baseline photos from follow-up photos in 55 out of 57 image pairs (96.5%). In assessments of rosacea, blinded reviewers scored 17 out of 19 participants with improvements greater than 40% and 11 out of 19 participants with improvements greater than 50%, with an average improvement of 53%. Side effects were limited to mild edema, mild to moderate erythema, and mild to moderate bruising, which resolved within a few days to 1 week.

“This long-awaited redesign of the PDL, a mainstay of cutaneous laser therapy for over a quarter-century, has enabled dramatically increased longevity of dye-kits, which should translate into even greater reliability in the field,” the researchers concluded. “The significantly larger diameter treatment beams with higher available fluences will reduce treatment times and should impact clinical results in a positive way.”

This study was funded by Syneron‐Candela. Bernstein is a consult and the 3 other authors are employed by Syneron‐Candela.

Reference

Bernstein EF, Schomacker K, Paranjape A, Jones CJ. Pulsed dye laser treatment of rosacea using a novel 15 mm diameter treatment beam [published online April 10, 2018]. Lasers Med Sci. https://doi.org/10.1002/lsm.22819.