Published in International Journal of Rheumatic Diseases, a study evaluated the relationship of fibromyalgia with enthesopathy, sleep, fatigue, and quality of life in patients with psoriatic arthritis (PsA).
Patients who met CASPAR criteria were included in the study, and demographic and clinical parameters were recorded. Fibromyalgia diagnosis was based on 2016 American College of Rheumatology criteria. Disease Activity Score-28 (DAS-28) and Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) were used to evaluate disease activity and enthesopathy, respectively. This study used a number of functional assessment scales, including Psoriatic Arthritis Quality of Life (PsAQoL), Pittsburgh Sleep Quality Index (PSQI), and Multidimensional Assessment of Fatigue (MAF), and the Fibromyalgia Impact Questionnaire (FIQ) was used to assess the functional status of fibromyalgia. Analysis was based on Mann-Whitney U tests and Spearman correlation coefficient (ρ), while hierarchical multiple regression analysis was utilized to examine the differential contributions to FIQ score.
In total, 50 (31 female, 19 male) patients were included with a mean age of 49.5 years (SD, 10.2) and mean disease duration of 7.5 years (SD, 7.5); 64% of patients fulfilled ACR criteria for fibromyalgia. Patients with fibromyalgia had significantly higher mean scores of MASES, PSQI, MAF, and PsAQoL (P<.05). In addition, there were significant correlations between FIQ and MASES (ρ=0.71; P<.0005), PSQI (ρ=0.62; P<.0005), MAF (ρ=0.60; P<.0005), and PsAQoL (ρ=0.61; P<.0005). A moderate correlation existed between FIQ and DAS-28 (ρ=0.42; P=.03).
The study concluded that the coexistence of fibromyalgia in patients with PsA is associated with the presence of enthesopathy, poor quality of life, sleep disturbance, and fatigue. —Jessica Garlewicz
Ulutatar F, Unal-Ulutatar C, Tuncay Duruoz M. Fibromyalgia in patients with psoriatic arthritis: Relationship with enthesopathy, sleep, fatigue and quality of life. Int J Rheum Dis. 2021;24(2):183-188. doi:10.1111/1756-185X.13963