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Low Cardiorespiratory Fitness in Late Adolescence Increases Long-Term Risk of Psoriasis and Psoriatic Arthritis

Low cardiorespiratory fitness in late adolescence is associated with the long-term risk of psoriasis and psoriatic arthritis (PsA) among men.

“Individuals with psoriasis have lower cardiorespiratory fitness compared with individuals without psoriasis,” explained the study authors. “There are no previous studies exploring the association between cardiorespiratory fitness and new-onset psoriasis and psoriatic arthritis,” they added.

Researchers investigated whether low cardiorespiratory fitness in late adolescence increases the risk for psoriasis and PsA in a cohort of Swedish men. Data were gathered from the Swedish Military Service Conscription Register. Cardiorespiratory fitness was divided into three groups (high, medium, and low) and compared with new-onset psoriasis or PsA.

A significant relationship between low cardiorespiratory fitness and psoriasis with a hazard ratio (HR) of 1.35 (95% CI, 1.26-1.44) and PsA with a HR of 1.44 (95% CI, 1.28-1.63) was reported.

“These novel findings suggest that low cardiorespiratory fitness at an early age is associated with increased risk of incident psoriasis and psoriatic arthritis among men, and highlight the importance of assessing cardiorespiratory fitness early in life,” concluded the study authors.

Reference
Laskowski M, Schiöler L, Gustafsson H, Wennberg AM, Åberg M, Torén K. Cardiorespiratory fitness in late adolescence and long-term risk of psoriasis and psoriatic arthritis among Swedish men. PLoS One. 2021;16(1):e0243348. doi:10.1371/journal.pone.0243348

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