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Does Gluten Intake Increase Risk for Inflammatory Diseases?

Gluten consumption was not associated with an increased risk for developing psoriasis, psoriatic arthritis (PsA), and atopic dermatitis (AD), according to the findings of a recent study.

In the study, the researchers examined data of women enrolled in the Nurses’ Health Study II. Food frequency questionnaires were used to determine the gluten content of participants’ diet every 4 years (1991 to 2015 for psoriatic disease and 1995 to 2013 for AD). Disease outcomes were assessed by self-report and subsequently validated by the researchers, and hazard ratios were calculated.
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A total of 85,185 participants were included in the psoriasis analysis, 85,324 were included in the PsA analysis, and 63,443 were included in the AD analysis.

The researchers found no association between increased gluten intake and any of the outcomes. Compared with the highest and lowest gluten intake quintiles, the multivariable HRs were 1.15 for psoriasis, 1.12 for PsA, and 0.91 for AD, the researchers said.

“Our findings do not support the amount of dietary gluten intake as a risk factor for psoriasis, PsA, or AD in adult women,” the researchers concluded.

Reference

Drucker AM, Qureshi AA, Thompson JM, Li T, Cho E. Gluten intake and risk of psoriasis, psoriatic arthritis and atopic dermatitis among US women [published online August 9, 2019]. J Am Acad Dermatol. doi:10.1016/j.jaad.2019.08.007

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