Alopecia Areata Linked to Several Comorbidities

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Alopecia areata is associated with several systemic and psychiatric diseases, according to the findings of a recent study. 

In the systematic review, researchers analyzed data from 87 studies that investigated the prevalence and incidents of various diseases among patients with alopecia areata.  
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They found that patients with alopecia areata had a higher prevalence of atopic diseases, metabolic syndrome, Helicobacter pylori infection, lupus erythematosus, iron deficiency anemia, thyroid diseases, psychiatric diseases, vitamin D deficiency, and audiologic and ophthalmic abnormalities. In addition, alopecia areata was associated with a higher risk for developing autoimmune diseases.

“Physicians are encouraged to evaluate and manage potential comorbid conditions to achieve better outcomes,” the researchers concluded.


Lee S, Lee H, Lee CH, Lee WS. Comorbidities in alopecia areata: a systematic review and meta-analysis [published online July 18, 2018]. J Am Acad Dermatol. doi:10.1016/j.jaad.2018.07.013