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Almost 10% of HS Patients Have Comorbid Inflammatory Eye Disease

Inflammatory eye disease may be independently associated with hidradenitis suppurativa (HS), according to the findings of a recent study.

The researchers sought to assess the spectrum and treatment outcomes of inflammatory eye disease among 236 participants with HS. They conducted a retrospective chart review of patients who underwent an ophthalmic examination between 2013 and 2018.

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Overall, 22 participants (9.3%) had inflammatory eye disease. Of these patients, 7 had more than one inflammatory eye disease diagnosis.

The most common type of inflammatory eye disease was anterior uveitis (40.9%), but the researchers also observed episcleritis, optic neuritis, keratitis, scleritis, intermediate and posterior uveitis, trochleitis, and dacryoadenitis.

In addition, 59.1% of participants with both HS and inflammatory eye disease did not have any other inflammatory or autoimmune diseases that could explain the etiology of their eye disease. In 3 participants, inflammatory eye disease was the principal factor directing treatment. systemic immunosuppressive was used to treat inflammatory eye disease in 11 patients.

“Inflammatory eye disease may be independently associated with HS and may benefit from systemic immunosuppression,” the researchers concluded.

Reference

Lee DJ, Desai S, Laurent E, Kopplin LJ. Characterization and management of inflammatory eye disease in patients with hidradenitis suppurativa [published online April 7, 2020]. Ocul Immunol Inflamm. doi:10.1080/09273948.2020.1739718

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