Volume 13 - Issue 6 - June 2005

Hyperkeratotic eczema of the hands and/or feet is a well recognized yet poorly understood entity that is typically chronic and refractory to therapy. The eruption is characterized by dry, thick, gray plaques involving the palmar and/or plantar surfaces. Features of acute or subacute eczematous dermatitis are not observed. Pruritus is usually noted, and when present, deep fissuring may lead to pain. Treatment of hyperkeratotic hand-foot eczema is often challenging. Response to topical corticosteroids, with or without occlusion, is not consistent and potent “keratolytic” therapy tends to provid