Volume 11 - Issue 2 - February 2003

T he most commonly encountered forms of nonmelanoma cutaneous epithelial malignancy include actinic keratosis (AK), basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Although not classically included in reported incidence estimates of nonmelanoma skin cancer, AKs are intraepithelial foci of malignancy representing the earliest clinical stage in the continuum of SCC development.1-3 Diagnosed in more than 47 million patient visits in the United States from 1990 to 1999, AK represents about 14% of dermatology visits, with more than 1 million new cases reported annually.1-5 SCCs have