Volume 10 - Issue 8 - August 2002

A 15-year-old male patient presented with ulcerated, erosive and nodular lesions on his face, back and chest. He’d been diagnosed with acne 1 year before and was originally treated by another physician with topical therapies and systemic antibiotics. Because his acne continued to worsen, he was started on isotretinoin 60 mg/day (Accutane). Two weeks after starting this treatment, he’d developed severe inflammation on his face, back and chest along with fever, myalgias and joint pain. He had been hospitalized for fever and leukocytosis, and treated with clarithromycin 250 mg b.i.d. (Biaxin), p