In recent study published in Pediatric Allergy and Immunology researchers set out to determine the impact of eczema severity on the development of these disorders and other non-atopic comorbidities in atopic dermatitis. The study used the 2007 National Survey of Children’s Health, a prospective questionnaire-based study of a nationally representative sample of 91,642 children aged 0 to17 years. Prevalence and severity of eczema, asthma, hay fever and food allergy, sleep impairment, healthcare utilization, recurrent ear infections and visual and dental problems were identified.
Severe eczema is associated with multiple comorbid chronic health disorders, impaired overall health and increased healthcare utilization, including seeing a specialist, compared with children with mild or moderate disease (Rao-Scott chi-squared test, P <0.0001), according to the researchers.
Specifically, the study demonstrated that severe eczema was associated with a higher prevalence of comorbid chronic health disorders, including asthma, hay fever and food allergies (P < 0.0001). In addition, the severity of eczema was directly related to the severity of the comorbidities. These associations remained significant in multivariate logistic regression models that included age, sex and race/ethnicity. Severe eczema was also associated with recent dental problems, including bleeding gums (P<0.0001), and toothache (P =0.0004), but not broken teeth (P=0.04) or tooth decay (P=0.13). Future studies are warranted to verify this novel association, they report.
Silverberg JI, Simpson EL. Association between severe eczema in children and multiple comorbid conditions and increased healthcare utilization. Pediatr Allergy Immunol. 2013;24(5):476-486.