OTC Antiperspirant Lotion for Treatment of Hyperhidrosis

Research in the United States in the early 2000s determined the hyperhidrosis (excessive sweating) prevalence rate to be 2.7% of the population.1

A recent study by Doolittle and colleagues2 found that the prevalence of hyperhidrosis in the United States is much larger—at a minimum, it is about 5% of the total population, but the authors noted that 5% is a very conservative estimate. International studies have shown that the prevalence of both primary and secondary hyperhidrosis abroad is significantly higher: 14% in Japan, 16% in Germany, 18% in Shanghai, and 20% in Sweden.2

Research conducted by the International Hyperhidrosis Society found that just under half of people with hyperhidrosis in the United States have not talked about it with a provider because they do not understand that it is a medical condition or do not realize that treatment options are available. Furthermore, the research found that more than 50% of patients who see a provider about hyperhidrosis remain undiagnosed.3

Prescriptions medications are available for the treatment of hyperhidrosis. However, they can be expensive, irritating, painful, and inconvenient.

Over-the-counter (OTC) Carpe Lotion, from Clutch Inc, is a dermatologist recommended, FDA compliant, nonirritating antiperspirant lotion that goes on smooth, leaves no residue, prevents sweaty hands and feet, and is affordable. It is the only OTC solution available to treat palmar and plantar hyperhidrosis. It also has a soothing eucalyptus scent that fades quickly after application.

After washing and drying hands and/or feet, individuals should apply a pea-sized amount of Carpe Lotion 2 to 3 times a day (once before bed and 2 more times during the day) for at least 4 weeks. Based on other studies that have been conducted on antiperspirants, effects compound significantly with extended use; therefore, individuals may be able to use the lotion less frequently as time progresses.

In addition to the recommended regimen for Carpe Lotion, the lotion is also safe to apply on an as-needed basis. The convenience of Carpe Lotion allows individuals to bring it with them to a meeting, date, or interview, and apply it beforehand to ensure they have the sweat-free hands.

Studies conducted by independent labs have shown Carpe Lotion to be 100% nonirritating and effective. Further research is needed to show the efficacy of the product after extended use. Another study with Carpe Lotion’s active ingredient (aluminum sesquichlorohydrate) in a topical solution showed a 61% sweat reduction after 4 weeks of using the product several times a week.4 The Dermatologist Product Spotlight provides a summary of the efficacy and tolerability studies in individuals with hyperhidrosis treated with Carpe Lotion. (Due to funding restraints, the efficacy study could only be conducted over 3 days.)

1. Strutton DR, Kowalski JW, Glaser DA, Stang PE. US prevalence of hyperhidrosis and impact on individuals with axillary hyperhidrosis: results from a national survey. J Am Acad Dermatol. 2004;51(2):241-248.
2. Doolittle J, Walker P, Mills T, Thurston J. Hyperhidrosis: an update on prevalence and severity in the United States. Arch Dermatol Res. 2016;308(10):743-749.
3. Glaser DA, Ballard AM, Hunt NL, Pieretti LJ, Pariser DM. Prevalence of multifocal primary hyperhidrosis and symptom severity over time: results of a targeted survey. Dermatol Surg. 2016;42(12):1347-1353.
4. Innocenzi D, Ruggero A, Francesconi L, Lacarrubba F, Nardone B, Micali G. An open-label tolerability and efficacy study of an aluminum sesquichlorohydrate topical foam in axillary and palmar primary hyperhidrosis. Dermatol Ther. 2008;21(suppl 1):S27-S30.

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